Rubella IgG
General information:
Rubella is primarily a childhood infectious disease with a viral cause and most often proceeds mildly with a rash, involvement of peripheral lymph nodes and minor intoxication symptoms. In case of illness of the pregnant woman in the first 20 gestational weeks of the pregnancy, damage to the fetus is also observed - embryopathies and fetopathies. Infection with rubella occurs through the air-droplet route. The rubella virus enters through the mucous membrane of the upper respiratory tract and the conjunctiva, reaching the lymph nodes, where it multiplies, via the lymphatic and blood routes. About 10 days after infection, the virus enters the blood again, through which it spreads to many tissues and organs, including the placenta. The peak of the spread of the rubella virus is around the 15-16th day of infection and is followed by the rash. Changes in the body in rubella are due to both the direct damaging effect of the virus and circulating immune complexes. Hormonal mechanisms are also possible in women.
Markers for rubella:
- Rubella IgM - when acute infection is suspected
- Rubella IgG - speaks of carriage and past infection. Remains for life.
Sample required:
Venous blood
Key words:
rubella IgM + IgG